Optic nerve radiation tolerance

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August undefined, 2024

WebRadiation tolerance of the optic pathway in patients treated with proton and photon radiotherapy In our study cohort, rates of RION were very low with conventionally fractionated RT up to 59 Gy. At doses ≥60 Gy, there is an increased risk of RION, with greater risk for women and older patients. WebOptical coherence tomography, or OCT, is an imaging method used to generate a picture of the back of your eye, called your retina. The noninvasive method produces an image by measuring the amount of a dim red light that reflects off of your retina and optic nerve. Optical coherence tomography can measure the thickness of your retina and optic ...

Long-Term Evaluation and Normal Tissue Complication …

WebAs radiation is commonly used for treatment of skull base and nasopharyngeal tumors, there is a lot of literature on PRCN involving lower (IX–XII) cranial nerves, reporting its … WebFeb 24, 2024 · Abstract and Figures. Purpose In radiotherapy, high radiation exposure to optic nerve (ON) can cause optic neuropathy or vision loss. In this study, we evaluated the pattern and extent of the ON ... darren hodgeson torquay

Proton Beam Therapy for Optic Nerve Sheath Meningioma EB

WebApr 1, 2003 · The range of maximum dose to the optic nerve or chiasm ranged from 0.4 to 16 Gy for a single procedure. Specifically, 58 (27%) received a maximum dose of < 8 Gy, … WebRadiation optic neuropathy (RON) is a rare complication of external beam radiation therapy (RT) in which exposure of the anterior visual pathway (AVP) to radiation results in acute, … WebFor a subset of patients with meningioma, the optic apparatus is dose limiting when considering single-dose stereotactic radiosurgery, with tolerance estimated to be 8 to 10 Gy. Recently, hypofractionated regimens have been used to treat benign meningiomas with a small number of fractions. darren hoffart lincoln ne

Long-Term Evaluation and Normal Tissue Complication …

Radiation dose-volume effects of optic nerves and chiasm

WebOct 1, 1992 · Radiation-induced optic neuropathy (RON) is a rare and catastrophic complication of currently employed radiation therapy regimens for meningiomas that have been partially resected and sampled for biopsy. WebMar 1, 2010 · Few studies have adequate data for dose-volume outcome modeling. The risk of toxicity increased markedly at doses >60 Gy at {approx}1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery. The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction. Models of threshold tolerance were examined. darren hill for douglas county sheriffWebThere can be many factors which will determine such tolerance, and these may include residual tissue injury present (the presence of residual stem or corrective cell depletion still present in the tissue); the interval between the two courses of radiation which will determine the extent of tissue regeneration; the volume of tissue required to … bison taxonomic domain

"WebJul 9, 2014 · Perhaps because of its innate, precarious blood supply, clinical experience has shown that the anterior visual pathways are especially sensitive to high doses of ionizing radiation. As a result, the risk of radiation injury to the optic nerves has engendered considerable angst in the setting of stereotactic radiosurgery (SRS). The general … " - Optic nerve radiation tolerance

Optic nerve radiation tolerance

Radiation Oncology/Toxicity/Emami - Wikibooks

WebNov 20, 2024 · Radiation damage to the optic nerve or chiasm may develop after whole-brain RT or focal RT for tumors in sites near the visual apparatus, ... et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 1991;21(1):109–122. WebPrevious surgery or radiation therapy was performed in 156 (66%) and 24 (11%) patients, respectively. Median follow-up was 40 months (range 4-115). Results: The median maximum radiation dose to the optic nerve was 10 Gy (range 0.4-16.0). Four patients (1.9%) developed RON at a median of 48 months after radiosurgery.

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WebMar 5, 2024 · RTOG Radiation Dose Constraints. Bladder [0534]: should be contoured from its base to the dome, excluding the CTV1 (the CTV1 includes the bladder neck). Rectum … WebJul 9, 2014 · As a result, the risk of radiation injury to the optic nerves has engendered considerable angst in the setting of stereotactic radiosurgery (SRS). The general …

WebThe WG includes physicists, radiation oncologists and radiation biologists and is charged with generating reports based on critical review of published data regarding both tumor and normal tissue response to the strongly hypofractionated regimens used in SBRT (SABR) treatments with suggestions for outcomes reporting standards that will facilitate … WebMay 24, 2024 · Optic nerve gliomas are benign tumors classified as pilocytic astrocytomas. They make up half of all primary optic nerve tumors and between 1.5 and 4% of all orbital tumors. Etiology Optic pathway gliomas …

WebJul 22, 2024 · The optic nerve head (also known as the optic disc) is approximately 1.5 mm wide and is also associated with a physiological cup that corresponds to a central depression in the optic nerve head. The … WebJun 14, 2024 · But sometimes radiation can damage the retina and optic nerve, leading to vision loss. These side effects can first appear up to 18 months after treatment and are …

WebJan 26, 2024 · Magnetic resonance imaging of the brain depicted bilateral prechiasmatic optic nerve enhancement with involvement of the optic chiasm. Treatment with high doses of corticosteroids was unsuccessful. ... Li PC, Liebsch NJ, Niemierko A, et al. Radiation tolerance of the optic pathway in patients treated with proton and photon radiotherapy ...

WebFeb 24, 2024 · In the patient’s original plan the D max of the optic nerve is approximately 52 Gy ( Table 2 ), which is within the tolerance limit; however, with the consideration of possible optic nerve movement, the D max could have increased to 56 Gy, falling into the range of increased risk (3-7%) for developing optic neuropathy (RION). FIGURE 4 darren holmes photographyWebAfter 20 years of RTOG trials, conventional radiation therapy had progressed to the point where Emami et al. 3 could, with relative certainty, pose the dose tolerance limits in terms of 5% or 50% chance of a specified adverse event occurring within five years. bison taxonomicWebFeb 24, 2024 · In the patient’s original plan the D max of the optic nerve is approximately 52 Gy ( Table 2 ), which is within the tolerance limit; however, with the consideration of … darren horger obituaryWebOptic neuropathy is a rare complication of cryptococcal meningitis and usually occurs in non-AIDS patients. Necrosis of the optic nerves and infiltration of the meninges around the optic tracts, nerves, and chiasm by cryptococcal organisms have been observed [ 8 ]. View larger version (66K) Fig. 7A —17-year-old boy with neuroschistosomiasis. darren hopman casper wyWebFeb 24, 2024 · The optic nerve is the second (CN II) cranial nerve (TA: nervus opticus or nervus cranialis II).It is a purely sensory nerve that conveys visual information from the eye to the brain.. The nerve arises … darren howard joineryWebJun 15, 2015 · WE-F-304-03: Optic Nerve/Chiasm Hypofractionated SRS/SRT Dose Tolerance Full Record Related Research Abstract Stereotactic Body Radiation Therapy (SBRT) was introduced clinically more than twenty years ago, and many subsequent publications have reported safety and efficacy data. darren howarthWebMay 1, 2024 · Optic apparatus NTCP and tolerance doses after single- and multi-fraction stereotactic radiosurgery are presented. Additional standardized dosimetric and toxicity … darren howe facebook