Cthrc1 kda
WebCTHRC1 was immunoprecipitated from 0.35 mg SK-MEL-28 (Human malignant melanoma) whole cell lysate with ab256458 at 1/30 dilution (2ug in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab256458 at 1/1000 dilution. VeriBlot for IP Detection Reagent (HRP) was used at 1/5000 dilution. WebImmunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human pancreas shows low positivity in glandular cells as expected. Immunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
Cthrc1 kda
Did you know?
WebFeb 9, 2012 · Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of colorectal cancer (CRC) since they have shown an increase messenger RNA transcripts (mRNA) expression level in adenomas and colorectal tumours when compared to normal … WebCTHRC1 is overexpressed in multiple human cancers, and its expression is associated with increased migration and metastasis, as well as decreased survival (1-3). CTHRC1 expression is regulated through TGF-β/Smad3 …
WebDec 23, 2004 · CTHRC1 is a secreted 28-kDa protein that is glycosylated and highly conserved from lower chordates to mammals. A short collagen motif with 12 Gly-X-Y repeats appears to be responsible for trimerization of the protein and this renders the molecule susceptible to cleavage by collagenase. WebOct 11, 2024 · Background Metastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation …
WebCTHRC1, a 28-kDa secreted ECM protein, could promote cell migration via limiting collagen matrix deposition [16]. ... (TAMs) is associated with tumor progression and poor prognosis in endometrial ... WebThe recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately …
WebAll lanes : Anti-CTHRC1 antibody (ab264410) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-3M whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band …
WebCollagen triple helix repeat containing 1: Protein class i. Disease related genes Human disease related genes: Predicted location i. Intracellular,Secreted ... 26.2 kDa Yes: 0: CTHRC1-202 ENSP00000416045 ENST00000415886: E7EVQ5 [Direct mapping] Collagen triple helix repeat-containing protein 1 . Show all. smart irb platformWebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. ... Highly conserved from lower chordates to mammals, the CTHRC1 protein was identified as a 30 kDa secreted protein and was first verified to be a differentially expressed gene in balloon-injured rat … hillside country cabins rapid cityWebCTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. smart irb sitesWebCTHRC1 is specifically expressed in vascular calcifications of carotid artery lesions and may contribute to vascular remodeling of injured arteries (Pyagay et al., 2005 [PubMed 15618538]).[supplied by OMIM] smart iron-on heat transfer vinylWebApr 17, 2024 · CTHRC1 has four different isoforms with molecular weights of about 12.3 kDa to 27 kDa; the full-length of CTHRC1 accounts for both secreted and cellular CTHRC1 . Glycosylated protein CTHRC1 with a … smart iron on heat transfer vinyl cricutWebCollagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein, reported to be involved in vascular remodeling, bone formation and morphogenesis [19]. In addition to functioning in the context of arterial injury, recent studies have reported CTHRC1 acts as a prognostic factor. Furthermore, it promotes tumor smart irrigation control sensor set gardenaWebCollagen triple helix repeat containing protein 1 (CTHRC1) is a 30 kDa secreted glycoprotein encoded by the CTHRC1 gene. CTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, hillside cromford campervans for sale